Fecal Microbiome Data for Tuberculosis Patients and Healthy Controls

Fecal microbiome data for tuberculosis (N=33) and healthy controls (N=47) is provided by Bayazit Yunusbayev. The dataset contains two phyloseq objects with relative abundances of bacterial species and metabolic pathways, processed using metaphlan 4.0 and HUMAnN 3.6. It was last updated on 2026-06-04.

Use Cases

• Compare bacterial species composition between TB patients and healthy controls based on relative abundance data.
• Analyze differences in microbial metabolic pathway activity between disease states based on Metacyc annotations.
• Train classifiers to distinguish TB patients from controls using microbiome profiles.
• Investigate correlations between specific bacterial species and metabolic functions mentioned in the description.

Strengths

• Includes data from 80 total samples (33 TB patients, 47 healthy controls).
• Provides two distinct data objects: one for species abundance and one for pathway abundance.
• Data processing methods (metaphlan 4.0, HUMAnN 3.6) and annotation sources (Metacyc) are specified.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is relatively small at 12.3 MB, which may constrain complex modeling.

Provenance

Source

Bayazit Yunusbayev via figshare

Collection Method

Inferred from fecal samples using metaphlan 4.0 for species and HUMAnN 3.6 for pathways.

Freshness

Last updated 2026-06-04 11:11:26; freshness should be verified.