Figure 2 – Source Data (spontaneous synaptic transmission and intrinsic properties in dmPF

979.0 KB of raw numerical values used to generate Figure 2 in a neuroscience study. The data, published by Jinseon Yu on figshare in April 2026, quantifies spontaneous synaptic events and intrinsic excitability in layer 2/3 pyramidal neurons of the dorsomedial prefrontal cortex following repeated ketamine treatment. It is structured in worksheets corresponding to specific figure panels.

Use Cases

• Reproduce statistical analyses and plots for synaptic event frequencies and amplitudes based on sIPSC and sEPSC recordings.
• Model neuronal excitability based on intrinsic properties like resting membrane potential, input resistance, and firing rates.
• Compare miniature excitatory postsynaptic current (mEPSC) properties in the presence of TTX based on inter-event intervals and amplitude data.
• Analyze the relationship between ketamine treatment and parvalbumin-positive (PV+) cell ratios in the dmPFC.

Strengths

• Data is directly linked to a specific published figure (Figure 2), enabling full reproducibility of its results.
• Includes multiple physiological measurement types: synaptic event properties, intrinsic excitability parameters, and cell ratios.
• Published under a CC-BY-4.0 license, allowing for reuse with attribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• The dataset's 979.0 KB size indicates a limited scope, likely containing summary or sample-level data rather than raw traces.

Provenance

Source

figshare, authored by Jinseon Yu.

Collection Method

Experimental recordings from layer 2/3 pyramidal neurons in the dmPFC of mice following repeated ketamine treatment.

Time Range

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Freshness

Last updated 2026-04-14 14:13:41; freshness should be verified.

Geography

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