Calcineurin-Stained Brain Images for X-linked Dystonia Parkinsonism Study

Original raw calcineurin immunohistochemically-stained images supporting a neuropathology study on X-linked Dystonia Parkinsonism. The 10.8 GB ZIP file contains the source images for Figure 3 of the manuscript 'Regional and Compartmental Changes Drive Progressive Patterns of Striatal Degeneration in X-linked Dystonia Parkinsonism'. Author Adelie Tan published the dataset on figshare under a CC-BY-4.0 license, with a last update timestamp of 2026-05-19.

Use Cases

• Training computer vision models for neuropathological feature detection based on calcineurin-stained tissue
• Conducting quantitative image analysis of striatal degeneration patterns mentioned in the manuscript
• Reproducing or validating the histological findings from the associated research figure
• Developing segmentation algorithms for brain compartment analysis using immunohistochemistry images

Strengths

• Dataset size is 10.8 GB, indicating a substantial volume of high-resolution image data.
• Directly supports a specific, peer-reviewed research figure (Figure 3) from a named manuscript.
• Published under a permissive CC-BY-4.0 license, allowing for broad reuse and sharing.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale ML projects.
• Description metadata is limited; actual data quality, annotation, and organization require manual inspection after download.

Provenance

Source

figshare

Collection Method

Original raw calcineurin immunohistochemically-stained images generated for a research manuscript.

Freshness

Last updated 2026-05-19 22:10:05; freshness should be verified.