Overchuk, Marta contributed this dataset to the ODUM Harvested Dataverse, last updated on 2026-06-08. The data describes lipid oxidation levels in OVCAR-3 and Caov-3 ovarian cancer cell lines following treatment with compounds ML210 and photodynamic therapy (PDT). It includes volcano plots, heatmaps, and box plots quantifying differentially expressed lipid hydroxides and hydroperoxides.
Use Cases
- Identify lipid species significantly altered by ML210 treatment based on volcano plot data.
- Compare the oxidative lipid profiles induced by ML210 versus PDT based on heatmap Z-scores.
- Validate specific oxidized lipid species upregulated by both treatments based on log2 fold-change box plots.
Strengths
- Data compares two distinct ovarian cancer cell lines (OVCAR-3 and Caov-3).
- Analysis includes multiple visualization types (volcano plots, heatmaps, box plots) for cross-validation.
- Treatments are applied at a specified dose (PDT at 1 J/cm2).
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- The dataset appears to be a single figure from a larger study, providing a focused snapshot.
Provenance
- Source
- Overchuk, Marta via ODUM Harvested Dataverse
- Collection Method
- Likely generated via mass spectrometry or similar lipidomic profiling of treated cell cultures.
- Freshness
- Last updated 2026-06-08 03:10:10; freshness should be verified.