Figure 6B: Mouse Antibody Titers Following repRNA/LION Immunization

Figure 6B contains antibody titer data from a mouse immunization study. The dataset, authored by Luqiang Guo and last updated in April 2026, includes measurements from female C57BL/6 mice immunized with repRNA/LION constructs at 1 or 10 μg doses. Blood was collected on days 0, 14, 35, and 49, and splenocytes were harvested at study termination.

Use Cases

• Analyzing antibody titer kinetics based on blood collection time points mentioned in the description
• Comparing immune responses based on vaccine dose levels (1 μg vs 10 μg) mentioned in the description
• Correlating systemic antibody data with cellular immune data based on the harvest of splenocytes mentioned in the description

Strengths

• Data is from a controlled animal study with 10 mice per group, as stated in the description
• Includes longitudinal measurements from four specific time points (days 0, 14, 35, 49)
• Released under a permissive CC-BY-4.0 license

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (10.8 KB), indicating limited scope

Provenance

Source

figshare, author Luqiang Guo

Collection Method

Data generated from a laboratory immunization study in mice, as described.

Time Range

Study timeline spans from day 0 to day 49 post-immunization.

Freshness

Last updated 2026-04-14 18:51:21; freshness should be verified

Geography

Laboratory study; geographic location is not specified.