Figure 6C: Mouse Antibody Response to RNA Vaccine Constructs Over 49 Days

A 49-day study of antibody titers in female C57BL/6 mice immunized with repRNA/LION vaccine constructs. The dataset, created by Luqiang Guo and last updated in April 2026, contains measurements from 10 mice per group, with blood collected at four time points and splenocytes harvested at termination.

Use Cases

• Modeling antibody titer kinetics based on dose and time points mentioned in the description
• Comparing immune response between 1 μg and 10 μg vaccine doses based on the experimental groups
• Analyzing the effect of a day 35 booster immunization on antibody levels
• Correlating terminal splenocyte data with serum antibody titers collected over the study

Strengths

• Experimental design includes 10 mice per group, providing a defined sample size
• Data collection spans four specific time points over a 49-day period
• License is CC-BY-4.0, permitting open reuse and modification

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset is very small (10.9 KB), indicating limited scope or summary-level data

Provenance

Source

figshare, author Luqiang Guo

Collection Method

Data likely generated from a controlled laboratory immunization study in mice.

Time Range

Study conducted over 49 days.

Freshness

Last updated 2026-04-14 18:51:18

Geography

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