Figure 6D: Mouse Serum Neutralization Titers for ANDV Vaccine Constructs

Day 0 to 49 longitudinal study of neutralizing antibody titers in female C57BL/6 mice immunized with repRNA/LION vaccine constructs. The dataset, created by Luqiang Guo and last updated in April 2026, contains serum 50% neutralization reciprocal titers measured at four time points after prime and boost vaccinations.

Use Cases

• Modeling antibody kinetics over time based on the longitudinal blood collection schedule
• Comparing dose-dependent immune responses based on the 1 μg and 10 μg immunization groups
• Analyzing the effect of a vaccine boost on neutralization titers based on the day 35 booster event

Strengths

• Controlled experimental design with 10 mice per group
• Longitudinal data with four specific measurement time points (days 0, 14, 35, 49)
• Explicitly licensed as CC-BY-4.0 for open reuse

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect experimental bias inherent to the specific mouse model and immunization protocol

Provenance

Source

Luqiang Guo via figshare

Collection Method

Experimental data from a mouse immunization study, likely generated via neutralization assays.

Time Range

Experimental timeline from day 0 to day 49.

Freshness

Last updated 2026-04-14 18:51:15; freshness should be verified

Geography

Laboratory study; geographic coverage is not specified.