Effects of Cannabidiol on Male and Female FSL Rats in Behavioral Tests

The dataset contains experimental results for figures 6 and 7 from a GraphPad Prism file. It describes the effect of cannabidiol (CBD) administered 1 or 2 hours before forced swim and open field tests. The data was generated by Gabriela Pandini Silote using Flinders Sensitive Line (FSL) rats, a model for depression.

Use Cases

• Compare behavioral despair responses between male and female rats based on the forced swim test results mentioned in the description.
• Analyze locomotor and exploratory activity changes based on the open field test results mentioned in the description.
• Investigate the time-dependent effects of cannabidiol administration based on the 1-hour and 2-hour pre-treatment intervals described.
• Model sex differences in pharmacological response using the separate male and female rat data indicated in the title.

Strengths

• Data is directly linked to specific published figures (6 and 7), providing traceability.
• Experimental design includes both male and female subjects and two distinct time points for drug administration.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Last update date is unknown; freshness unverified.

Provenance

Source

Gabriela Pandini Silote via paperswithcode

Collection Method

Experimental data from behavioral tests (forced swim test, open field test) on Flinders Sensitive Line rats.