FKBP8 Inhibits Influenza A Virus Infection by Degrading Viral M2 Protein

A 6.1 MB dataset from figshare, last updated on 2026-05-29. It contains research data investigating the role of host protein FKBP8 as a restriction factor against Influenza A virus. The data, authored by Linyue Lv, details mechanisms of viral M2 protein degradation via the lysosomal pathway.

Use Cases

• Modeling host-pathogen protein-protein interactions based on the described FKBP8-M2 binding.
• Analyzing lysosomal degradation pathways for viral proteins based on the described FKBP8-RAB7A-LAMP1-M2 complex.
• Screening for broad-spectrum antiviral host factors based on FKBP8's interaction with other enveloped RNA virus proteins.
• Validating viral entry inhibition mechanisms based on the described role of FKBP8 in viral uncoating.

Strengths

• Dataset is 6.1 MB in size, indicating a focused and manageable download.
• License is CC-BY-4.0, permitting broad reuse with attribution.
• Description provides a detailed mechanistic study of a specific antiviral host factor.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Sample data is unavailable, preventing preview of data structure.

Provenance

Source

figshare

Collection Method

Likely contains experimental data from virology research, as described.

Freshness

Last updated 2026-05-29 11:26:06; freshness should be verified.