Frugal Sampling Strategies for Metal-Catalyzed Cross-Coupling Reactions

Novel high-throughput experimentation sampling strategies require only 25% of the experiments compared to full factorial designs. Vincent Porte authored this dataset, which applies frugal sampling to four challenging metal-catalyzed cross-coupling reactions. The dataset was last updated on April 10, 2026.

Use Cases

• Optimizing metal-catalyzed cross-coupling reactions based on frugal sampling strategies
• Training Bayesian optimization models based on cost-penalized yield objectives
• Analyzing chemical reaction trends based on quasi-random sampling methods
• Designing efficient 96-well microtiter plate layouts based on maximized diversity

Strengths

• Sampling strategies require only 25% of experiments compared to full factorial designs
• Applied to four challenging metal-catalyzed cross-coupling reactions
• Methods are designed for practicality on 96-well microtiter plates

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment

Provenance

Source

figshare

Collection Method

High-throughput experimentation (HTE) sampling applied to chemical reactions.

Freshness

Last updated 2026-04-10 11:39:17