MIPS Protein Complex Topological Survey Results

Full results from a topological survey of protein complexes in the MIPS database. The data includes separate spreadsheets for the full interaction graph, a pruned 'haircut' subgraph, and a highly connected 'max connect' subgraph, with complexes categorized by their connectivity. Author Suzanne Renick Gallagher compiled the statistics, which are available under an Open Access license.

Use Cases

• Compare topological properties of protein complexes based on different graph representations (Normal, Haircut, Max Connect).
• Identify protein complexes with no recorded interactions in the Yeast Two-Hybrid (Y2H) data for further experimental validation.
• Analyze the connectivity of complexes by separating those that induce connected subgraphs from those that do not.

Strengths

• Data is structured into multiple logical spreadsheets (Normal, Haircut, Max Connect, No Interaction) for comparative analysis.
• Includes a dedicated list of complexes with no interactions in the Y2H data, highlighting potential data gaps.
• Results are derived from the established MIPS database of protein complexes.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Last update date is unknown; freshness unverified.

Provenance

Source

MIPS database and associated Yeast Two-Hybrid (Y2H) data.

Collection Method

Topological survey and statistical analysis of protein complex interaction graphs.