Gelatin/PEG/g-C3N4 Hydrogel Nanocarrier Properties for 5-FU Delivery

A dataset from a research project on a pH-sensitive nanocomposite for targeted drug delivery against breast cancer. The nanovehicle, based on graphitic carbon nitride coated with Gelatin and Polyethylene glycol, was prepared using a W/O/W double emulsion technique with olive oil. The dataset likely contains measurements of nanoparticle size, zeta potential, drug loading efficiency, release kinetics, and cytotoxicity results from MTT assays and flow cytometry.

Use Cases

• Modeling drug release kinetics based on pH-dependent release rates mentioned in the description
• Analyzing nanoparticle stability based on zeta potential and size distribution data
• Comparing drug loading and encapsulation efficiency across different nanocarrier formulations
• Evaluating cytotoxicity and apoptotic effects of drug-loaded nanocomposites on cancer cell lines

Strengths

• Specific drug loading (47%) and encapsulation efficiency (89%) metrics are reported
• Nanoparticle size range (250-300 nm) and zeta potential (+35.4 mV) provide key physical characterization
• Includes comparative release rate data at pH 5.4 versus pH 7.4, simulating cancerous and physiological environments

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data scope is limited to a specific nanocomposite formulation and MCF-7 breast cancer cell line

Provenance

Source

Rahmani, Milad via e-cienciaDatos Harvested Dataverse

Collection Method

Experimental data from synthesis and characterization of a nanocomposite drug delivery system.

Time Range

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Freshness

Last updated 2025-10-14 21:29:44; freshness should be verified

Geography

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