Methanobrevibacter Intestini G0370_i3: Genomic and Phenotypic Data

A dataset from 2026 provides genomic and phenotypic characterization of the human gut archaeon Methanobrevibacter intestini strain G0370_i3, isolated from a healthy adult in Southern Gabon. It includes genome sequence data, phenotypic growth profiles, and stress tolerance assays. The data highlights metabolic capabilities, mobile genetic elements, and stress resilience traits of a strain from an underrepresented African population.

Use Cases

• Comparative genomics analysis based on the annotated genome sequence and identified mobile genetic elements.
• Studying metabolic adaptation in methanogens using data on H2/CO2 and formate growth pathways.
• Investigating microbial stress resilience using phenotypic data on antibiotic, salt, and oxygen tolerance.
• Exploring host-microbe interaction mechanisms through analysis of encoded adhesin-like proteins.

Strengths

• Includes detailed phenotypic characterization, such as optimal growth at 37°C and tolerance to specific stresses.
• Genome annotation identifies 23 mobile genetic elements and 5 defense systems, providing insights into horizontal gene transfer.
• Explicitly represents an African population, addressing a gap in microbiome research diversity.

Limitations

• Dataset scale is limited to a single isolated strain (G0370_i3).
• Column names and a precise row count are not provided, limiting understanding of data structure.
• Metadata is sparse regarding the specific experimental methods for phenotypic assays.

Provenance

Source

Mirabeau Mbong Ngwese

Collection Method

Strain was enriched from human stool, phenotypically characterized, and sequenced.

Freshness

Last updated on 2026-03-20.

Geography

Southern Gabon, Africa