Clostridioides difficile RT027 Isolates from China: Genomic and Phenotypic Data

11 RT027 isolates were collected from Shandong, China and analyzed using whole-genome sequencing, comparative transcriptomics, CRISPR-Cas analysis, and pan-genome profiling. Phenotypic assays measured toxin production, sporulation, antimicrobial resistance, and motility. The dataset was authored by Wenjia Wang and last updated on 2026-03 -17.

Use Cases

• Comparative genomic analysis of virulence factors based on the presence of tcd and cdt loci.
• Studying antimicrobial resistance patterns based on the reported rifamycin and aminoglycoside resistance genes.
• Analyzing evolutionary divergence and lineage formation based on the described phylogenetic relationship to FQR1.
• Investigating the correlation between gene expression (e.g., cdtAB, spo0A) and phenotypic traits like sporulation and motility.

Strengths

• Includes multi-omics data from 11 isolates, combining genomic, transcriptomic, and phenotypic assays.
• Provides specific findings on gene presence (complete tcd and cdt loci) and resistance genes.
• Dataset is 6.5 MB in size, making it relatively quick to download and inspect.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The sample size of 11 isolates may limit the generalizability of findings.

Provenance

Source

figshare, authored by Wenjia Wang.

Collection Method

Whole-genome sequencing, comparative transcriptomics, CRISPR-Cas analysis, pan-genome profiling, and phenotypic assays on collected isolates.

Time Range

null

Freshness

Last updated 2026-03-17 17:00:46; freshness should be verified.

Geography

Shandong, China