Gold Anticancer Complexes: A Review of Au(I/III) Compounds and Ligand Structures

A review paper discusses gold(I) and gold(III) complexes for their anticancer properties, contrasting them with conventional platinum compounds. The author, Giset Y. Sánchez Delgado, compiled this overview from published research, focusing on complexes with phosphine and N-heterocyclic carbene ligands. The paper is available under an Open Access license via the paperswithcode platform.

Use Cases

• Literature review on gold-based anticancer agents based on the described compound classes.
• Analysis of structure-activity relationships for gold complexes based on ligand types mentioned.
• Comparative study of anticancer mechanisms between gold and platinum compounds based on the described properties.
• Identification of potential therapeutic targets for gold complexes based on the review's discussion.

Strengths

• Focuses on a specific and active research area in medicinal chemistry.
• Provides a comparative analysis against conventional platinum anticancer compounds.
• Discusses specific ligand types (phosphines, N-heterocyclic carbenes) and their roles.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Likely a literature review compiled from published scientific research.