Mouse Liver Metabolomics and Lipidomics Data from GPR146 Study

Processed liver metabolomics and lipidomics data generated from mouse liver tissue to investigate metabolic changes associated with GPR146 depletion. Haojie Yu published the dataset on figshare in April 2026. The data comprises quantitative output tables from four complementary liquid chromatography–mass spectrometry platforms.

Use Cases

• Comparative analysis of hepatic metabolomic profiles based on processed quantitative output tables
• Investigating lipidomic changes in liver tissue based on complex lipid profiling data
• Studying metabolic pathway alterations based on polar metabolite data from HILIC platforms
• Analyzing free fatty acids and bile acids based on reversed-phase C18 chromatography data

Strengths

• Data processed using four complementary LC-MS platforms, including HILIC and reversed-phase methods
• Metabolite and lipid identities confirmed using authentic reference standards or reference samples
• Data processed using TraceFinder, Progenesis QI, and MultiQuant software following vendor- and community-standard workflows

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is specific to mouse liver tissue and a single experimental condition

Provenance

Source

figshare

Collection Method

Liver homogenates analyzed using LC-MS platforms; processed by an institutional metabolomics core facility.

Freshness

Last updated 2026-04-10 07:05:33