Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults
by Jonathan E. Kaplan / CDC Foundation
Available on 1 platform
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Description
A report updating guidelines for preventing and treating opportunistic infections in HIV-infected adults and adolescents, prepared by the CDC, NIH, and HIVMA/IDSA. The guidelines cover epidemiology, diagnosis, prevention, treatment, and special considerations for multiple OIs, including those acquired during international travel. Recommendations are rated by strength and evidence quality, with major updates emphasizing antiretroviral therapy and new diagnostic methods.
Use Cases
Training clinical decision support systems based on the structured recommendations and evidence ratings.
Analyzing guideline evolution for opportunistic infection management based on the 2007 update from earlier 2002/2004 versions.
Studying the integration of antiretroviral therapy into OI prevention protocols as a major guideline change.
Extracting information on drug interactions, particularly involving rifamycin drugs for tuberculosis, for pharmacovigilance applications.
Strengths
Guidelines are developed by a panel of specialists from major US government and academic institutions (CDC, NIH, HIVMA/IDSA).
Recommendations are systematically rated by a letter for strength and a Roman numeral for evidence quality.
The report includes eleven tables and a figure pertinent to the prevention and treatment of OIs.
Limitations
The underlying data format and structure (e.g., columns, rows) are unknown, limiting technical assessment.
The last update date is unknown; the guidelines are based on a review meeting in June 2007, so clinical recommendations may be outdated.
Column-level documentation is absent; field semantics must be inferred after download.
Provenance
Source
Centers for Disease Control and Prevention (CDC), National Institutes of Health (NIH), and the HIV Medicine Association (HIVMA) of the Infectious Diseases Society of America (IDSA).
Collection Method
Developed by a specialist panel through literature review and consensus meetings, with final approval by the listed organizations.
Time Range
Guidelines updated as of June 2007, superseding versions from 2002 and 2004.
Geography
Primarily intended for use in the United States, with some coverage of infections acquired during international travel.
License is closed, restricting redistribution and commercial use.