Beta-Hairpin Antimicrobial Peptide Sequence Families and Characteristics

27 unique macrocyclic β-hairpin antimicrobial peptide sequence families are cataloged from the literature. The dataset, compiled by Rabina Ramtel and last updated in March 2026, analyzes sequence composition and common characteristics. It is a small, focused collection of 24.5 KB stored in an Excel file.

Use Cases

• Training sequence-based machine learning models based on the 11–25 amino acid length and cationic charge characteristics.
• Analyzing residue enrichment patterns based on the strong preference for arginine over lysine.
• Identifying potential new β-hairpin AMPs based on the defined sequence characteristics like cysteine pair separation.
• Comparative analysis of peptide families based on the breakdown by structural region.

Strengths

• Focuses on a specific, rare peptide class with fewer than 30 identified families.
• Provides analyzed sequence characteristics including length range (11–25 amino acids) and charge properties.
• Explicitly lists 27 unique sequence families from a literature review.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 24.5 KB size indicates a very limited scope of data.

Provenance

Source

figshare, author Rabina Ramtel

Collection Method

Compiled from a literature review.

Freshness

Last updated 2026-03-19 12:07:00; freshness should be verified.