Heparin-Functionalized Nanoparticle Characterization Images for Malaria Drug Delivery

353.2 nm nanoparticles loaded with quinine show a 5.3-fold higher antiplasmodial potency and 14.2-fold greater selectivity index compared to free drug. This dataset contains characterization images from a study developing targeted nanomedicine for malaria therapy, authored by Yohana Amos and uploaded to figshare in April 2026. The data likely includes results from physicochemical analysis, in vitro drug release, and antiplasmodial activity tests against the FCR3 Plasmodium falciparum strain.

Use Cases

• Analyze nanoparticle physicochemical properties based on size, PDI, and zeta potential data mentioned in the description
• Model in vitro drug release kinetics based on the sustained release over 96 hours via Fickian diffusion
• Evaluate targeted drug delivery efficacy based on the increased infected RBC targeting partition ratio
• Compare antiplasmodial potency and selectivity based on the reported IC50 and selectivity index values

Strengths

• Specific nanoparticle characterization metrics are provided, including size (353.2 nm), PDI (0.252), and encapsulation efficiency (77.9%)
• Biological efficacy metrics are quantified, showing a 5.3-fold higher antiplasmodial potency and 14.2-fold greater selectivity index
• Data is openly shared under a CC-BY-4.0 license, facilitating reuse and collaboration

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• The dataset consists of PNG images (26.3 MB), which may require specialized tools for quantitative analysis

Provenance

Source

figshare

Collection Method

Data generated from laboratory experiments formulating and testing nanoparticles, likely using a double emulsion solvent evaporation technique.

Time Range

Experimental timeframe is not specified.

Freshness

Last updated 2026-04-14 10:42:25; freshness should be verified

Geography

Study context is global health, with specific mention of sub-Saharan Africa, but geographic data coverage is not specified.