HSFA2: Arabidopsis Gene Expression in Spaceflight Microgravity

Microarray gene expression data from Arabidopsis thaliana cell cultures grown aboard the International Space Station. The data compares wild-type and HSFA2 knock-out lines to analyze physiological adaptation to microgravity. The experiment was part of the BRIC17 mission's Cellular Expression Logic (CEL) experiment, with samples fixed after 10 days on orbit.

Use Cases

• Identify differentially expressed genes between spaceflight and ground environments based on the comparative analysis described.
• Study the role of the HSFA2 gene in cellular adaptation to microgravity based on genotype comparisons.
• Investigate endoplasmic reticulum stress and unfolded protein response pathways in genetically modified plant cells.
• Analyze gene networks involved in cell wall remodeling, signal transduction, and starch biosynthesis under spaceflight conditions.

Strengths

• Data originates from a controlled spaceflight experiment aboard the International Space Station.
• Analysis uses a two-part comparative approach (environment and genotype) as described.
• Dataset is provided by the National Aeronautics and Space Administration (NASA).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count and dataset size are unknown, which may limit suitability assessment.
• Data is provided in a BIN file format, which may require specific tools for access.

Provenance

Source

National Aeronautics and Space Administration

Collection Method

Microarray analysis of Arabidopsis thaliana cell cultures from the BRIC17 spaceflight mission's CEL experiment.

Freshness

Last updated 2026-03-13 19:28:58.900704; freshness should be verified.

Geography

International Space Station (orbital)