Hyperthyroidism and COVID-19: A Review of ACE2 Interactions

A review article authored by Nathalia Senger from Universidade de São Paulo. It discusses the potential cross-talk between hyperthyroidism and COVID-19, focusing on the role of the angiotensin-converting enzyme 2 (ACE2) receptor. The review highlights known and unknown features of COVID-19 related to ACE2 and hyperthyroidism, noting a lack of consistent clinical and experimental evidence.

Use Cases

• Identify potential research gaps based on the review of ACE2 upregulation in hyperthyroidism.
• Inform clinical study design based on the described association between cardiovascular disease and COVID-19 mortality.
• Guide literature review on SARS-CoV-2 entry mechanisms based on the discussion of ACE2 as a coreceptor.

Strengths

• Authored by a researcher from Universidade de São Paulo.
• Focuses on a specific, under-researched interaction between a viral infection and an endocrine disorder.

Limitations

• The dataset is a single review article, not a collection of primary data.
• Row count and column-level documentation are absent.
• Last update date is unknown; freshness unverified.

Provenance

Source

paperswithcode

Collection Method

Authored review article.

Geography

Initial data from Wuhan, China; author based in Brazil.