Hyperuricemia in Down Syndrome Children, 139 Patients Aged 1-14 Years

28.1% of 139 Down syndrome children and adolescents in a retrospective study had serum uric acid levels above the normal value. The sample included 70 males and 69 females with a mean age of 5.31 years. This dataset, sourced from a paper by Renato Nisihara, examines the prevalence of hyperuricemia and its distribution by age and gender.

Use Cases

• Assessing hyperuricemia prevalence based on age groups mentioned in the description
• Analyzing gender differences in serum uric acid levels, particularly in the 13-15 year range
• Modeling hyperuricemia as a risk factor for atherosclerotic heart disease in Down syndrome patients

Strengths

• Includes data for 139 patients, providing a specific sample size
• Reports detailed demographic breakdowns: 50.4% males and 49.6% females
• Contains specific statistical findings, such as a p-value of 0.02 for gender differences in the 13-15 year age group

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count for the underlying dataset is unknown, which may limit suitability assessment
• Last update date is unknown; freshness unverified

Provenance

Source

Renato Nisihara via paperswithcode

Collection Method

Retrospective study of patient records