Rat Colon and Systemic Toxicity Data from Combined Methylmercury and Microplastic Exposure

A figshare-hosted dataset by Henrique Mautone Gomes, last updated May 2026, containing experimental results from a rat model study. The 51.4 MB dataset includes TIF and DOCX files documenting the effects of 8-week exposure to 0.5 mg/L methylmercury and 0.2 mg/L polystyrene microplastics. It provides in vivo evidence of colon barrier disruption, gut dysbiosis, and systemic oxidative imbalance resulting from co-exposure.

Use Cases

• Analyzing histopathological changes in colon tissue based on TIF image files mentioned in the description
• Studying gut microbiome dysbiosis and diversity indices based on the described microbial composition data
• Modeling systemic oxidative stress and cytokine responses based on described biochemical and serum cytokine measurements
• Investigating the synergistic toxicity of microplastics and heavy metals based on the described co-exposure experimental design

Strengths

• Dataset size is 51.4 MB, providing a manageable download for inspection
• Experimental design uses 64 rats across 4 groups, providing a controlled comparison
• Exposure doses (0.5 mg/L MeHg, 0.2 mg/L PS-MP) are described as environmentally relevant
• Study duration of 8 weeks allows for observation of chronic effects

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data may reflect experimental bias inherent to the specific animal model and exposure protocol

Provenance

Source

figshare

Collection Method

Experimental data from an in vivo rat study with controlled contaminant exposure.

Time Range

Experimental period involved 8 weeks of exposure.

Freshness

Last updated 2026-05-06 07:14:04; freshness should be verified

Geography

Geographic origin of the study or data is not specified.