Eriс Khananshvilli published an exploratory study on figshare in 2026 demonstrating RNA targeting in the nematode Caenorhabditis elegans. The dataset likely contains results from experiments where cholesterol-conjugated DNAzymes were delivered by feeding to reduce target gene expression in intestinal cells. The data is available under a CC-BY-4.0 license.
Use Cases
- Validate DNAzyme design principles based on cholesterol conjugation requirement
- Assess gene silencing efficacy based on fluorescence reporter reduction
- Model cellular uptake mechanisms based on delivery method
- Benchmark non-toxic RNA manipulation tools based on observed health effects
Strengths
- Dataset is openly licensed (CC-BY-4.0)
- File is a structured XLSX format (26.3 KB)
- Description provides a clear proof-of-principle demonstration
Limitations
- Row count is unknown, which may limit suitability assessment
- Column-level documentation is absent; field semantics must be inferred after download
- Dataset scale is small (26.3 KB), indicating limited scope
Provenance
- Source
- figshare
- Collection Method
- Experimental results from in vivo RNA targeting studies in C. elegans.
- Freshness
- Last updated 2026-05-25 12:05:33; freshness should be verified