Lactobacillus Acidophilus Membrane Vesicle Activity Against Streptococcus Mutans

A study by Venkatramanan Mahendrarajan investigates the antimicrobial effects of membrane vesicles (MVs) from Lactobacillus acidophilus on the oral pathogen Streptococcus mutans. The dataset includes in vitro and in vivo experimental results, with proteomic analysis suggesting the presence of antimicrobial peptides. The data was last updated on April 29, 2026.

Use Cases

• Analyze antimicrobial properties of membrane vesicles based on in vitro screening results mentioned in the description
• Study biofilm formation prevention based on experimental data against Streptococcus mutans
• Investigate virulence gene expression (brpA, comDE, spaP) based on reported reduction levels
• Explore potential therapeutic peptides based on proteomics findings referenced in the description

Strengths

• Includes both in vitro and in vivo experimental data, strengthening the significance of findings
• Proteomic study cross-referenced with the DBAASP database for peptide identification
• Data is shared under a permissive CC-BY-4.0 license

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• The dataset is relatively small at 9.6 MB, potentially limiting scope

Provenance

Source

figshare

Collection Method

Experimental research involving membrane vesicle isolation, antibacterial screening, and proteomic analysis.

Freshness

Last updated 2026-04-29 11:20:04; freshness should be verified