Integrin αVβ5 Adhesion Dynamics and Cell Migration Data

Supporting data for a study on the dynamic transformation between focal adhesions and reticular adhesions. The dataset, authored by Tsun Chiu Lee and last updated on 2026-05-19, likely contains measurements related to integrin subunit ratios, protein recruitment, and cell motility on vitronectin-coated surfaces.

Use Cases

• Modeling the transition between focal adhesions and reticular adhesions based on talin and Dab2 protein levels.
• Analyzing the relationship between integrin αV/β5 subunit ratios and adhesion structure type.
• Investigating the role of specific integrin β5 domains in adhesion formation using domain-swapping chimera data.
• Correlating adhesion type (FA vs. RA) with cell migration speed.

Strengths

• Data supports a peer-reviewed study elucidating a specific biological mechanism.
• Includes results from FRET and pixelwise analyses to validate molecular interactions.
• Last updated on 2026-05-19, indicating recent maintenance.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect experimental bias inherent to the specific cell culture and vitronectin-coating methodology.

Provenance

Source

figshare, authored by Tsun Chiu Lee.

Collection Method

Likely generated from cell biology experiments involving fluorescence microscopy, FRET, and molecular biology techniques.

Freshness

Last updated 2026-05-19 01:29:19; freshness should be verified.