IgA Vasculitis with Necrotizing Arteritis: Clinical Data from a Multicenter Study

A multicenter retrospective study from the French Vasculitis Study Group characterizes IgA vasculitis with necrotizing arteritis (IgAV-NA). The dataset includes 30 patient cases and compares clinical features, treatments, and outcomes with 257 adult IgAV and 196 polyarteritis nodosa patients. The work combines original data with a systematic literature review spanning 1990–2025.

Use Cases

• Compare clinical phenotypes between IgA vasculitis with necrotizing arteritis and classical IgA vasculitis based on described severe manifestations.
• Analyze mortality and complication rates in IgA vasculitis with necrotizing arteritis versus polyarteritis nodosa based on the provided patient cohorts.
• Identify risk factors for severe gastrointestinal and neurological involvement in vasculitis based on the described clinical features.

Strengths

• Includes data from a multicenter study combined with a systematic literature review, covering 1990–2025.
• Compares 30 IgAV-NA cases against 257 adult IgAV and 196 PAN control patients.
• Clinical features are detailed, including severe manifestations like gastrointestinal bleeding, perforation, and neuropathy.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small in scale (402.4 KB), indicating limited scope.

Provenance

Source

French Vasculitis Study Group

Collection Method

Multicenter retrospective study combined with a systematic literature review.

Time Range

1990–2025

Freshness

Last updated 2026-05-27 04:40:04; freshness should be verified.

Geography

Likely France-based, but specific geography is not stated.