IHEC gABC-scores: Enhancer-Gene Interactions from H3K27ac ChIP-seq

IHEC gABC-scores contain enhancer-gene interactions called using the generalised Activity-by-Contact score on H3K27ac ChIP-seq data from the International Human Epigenome Consortium. The dataset is 3.0 GB in size and was last updated on 2026-05-10. It was authored by Juliana Estefanía Arcila Galvis and is shared under a CC-BY-4.0 license.

Use Cases

• Predicting enhancer target genes based on the generalised Activity-by-Contact score.
• Analyzing regulatory networks using called enhancer-gene interactions.
• Integrating with other IHEC datasets to study epigenetic regulation.
• Validating computational models of chromatin interaction and gene activity.

Strengths

• Dataset is 3.0 GB, indicating a substantial volume of interaction data.
• Derived from the authoritative IHEC H3K27ac ChIP-seq data source.
• Uses a defined computational method (generalised Activity-by-Contact score) for calling interactions.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

International Human Epigenome Consortium (IHEC) H3K27ac ChIP-seq data.

Collection Method

Computational calling using the generalised Activity-by-Contact score.

Freshness

Last updated 2026-05-10 16:03:01; freshness should be verified.