Mouse Popliteal Lymph Node Vascular Structure Images from Phase-Contrast Synchrotron µCT

Mohammad Jafarnejad provides a collection of 3D image stacks showing the vascular structure of four mouse popliteal lymph nodes. The images were derived using phase-contrast synchrotron micro-computed tomography (µCT) after a corrosion casting technique with Mercox II resin. The related study aimed to quantify vessel surface area distribution to understand transport phenomena down to the cell-level scale.

Use Cases

• Training 3D image segmentation models for blood vessels based on the high-resolution µCT image stacks.
• Developing algorithms for vessel skeletonization and diameter calculation based on the described binary data processing pipeline.
• Estimating blood flow pressures and velocities in micro-vasculature based on the Poiseuille flow assumption mentioned in the methodology.
• Validating computational models of lymph node transport phenomena based on the spatially-resolved 3D data on vessel distribution.

Strengths

• Data consists of high-resolution 3D image stacks derived from phase-contrast synchrotron µCT, a specialized imaging technique.
• Includes vascular structure from four distinct mouse lymph nodes, providing a small sample for comparison.
• The related methodology is described in detail, including steps from casting to segmentation and flow estimation.

Limitations

• Dataset scale is limited to four lymph node samples, which may not support large-scale statistical analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

Mohammad Jafarnejad

Collection Method

Phase-contrast synchrotron micro-computed tomography (µCT) of corrosion-cast mouse lymph nodes, with image reconstruction and processing.