Immunogenicity in Sheep of Uruguayan Bovine Virus Vaccines

Serological responses from 37 sheep immunized with four commercial Uruguayan vaccines against bovine alphaherpesviruses and pestiviruses. The study evaluated neutralizing antibody titers at five intervals post-vaccination over 90 days. The dataset likely contains results from this immunological trial, authored by Ingryd Merchioratto.

Use Cases

• Compare vaccine performance based on geometric mean titers (GMT) reported in the description
• Model antibody decay over time based on measurements at days 0, 25, 40, 60, and 90 post-vaccination
• Analyze seroconversion rates based on the percentage of animals achieving protective titers (GMT > 8)
• Evaluate cross-reactivity and specific immune responses to different viral strains (BoHV-1, BoHV-5, BVDV-1, BVDV-2, HoBiPeV)

Strengths

• Data is derived from a controlled study with 37 animals and five measurement time points
• Results include specific geometric mean titers (e.g., GMT 2.2, GMT > 8) and seroconversion percentages (e.g., ~70%)
• Directly compares the immunogenic performance of four distinct commercial vaccine formulations

Limitations

• Row count and column-level documentation are absent; field semantics must be inferred after download
• Last update date is unknown; freshness unverified
• Data may reflect geographic bias inherent to the study's focus on Uruguayan commercial vaccines

Provenance

Source

paperswithcode

Collection Method

Experimental trial involving immunization and serological testing of sheep.

Time Range

The study period covered 90 days post-vaccination.

Geography

Uruguay (focus on Uruguayan commercial vaccines)