Meta-Analysis of Post-Operative Atrial Fibrillation Outcomes After Cardiac Surgery

A systematic review and meta-analysis quantifies the association between post-operative atrial fibrillation and adverse outcomes after cardiac surgery. The work includes 54 studies covering 623,962 patients and reports risk ratios for mortality, stroke, and acute kidney injury. It was authored by Ibrahim Khalil and published on figshare in May 2026.

Use Cases

• Assess the risk of early mortality associated with POAF based on the reported relative risk of 1.94.
• Investigate the association between POAF and stroke risk based on the reported relative risk of 1.39.
• Identify effect modifiers like prior stroke prevalence through the meta-regression analysis described.
• Evaluate the certainty of evidence for POAF outcomes using the GRADE framework results mentioned.

Strengths

• Analysis is based on a substantial patient population of 623,962 from 54 studies.
• Employs multiple analytical methods including trial sequential analysis, Bayesian analysis, and meta-regression.
• Evidence certainty is formally assessed using the GRADE framework.

Limitations

• The dataset is a 427.7 KB document collection; no structured data files are available for direct computational analysis.
• Column-level documentation is absent; field semantics must be inferred from the PDF/DOCX documents.
• The underlying data's geographic and temporal coverage is not specified.

Provenance

Source

figshare

Collection Method

Systematic review and meta-analysis of studies from PubMed, Embase, CENTRAL, and Web of Science.

Time Range

Studies searched through December 2024.

Freshness

Last updated 2026-05-11 07:53:15.