Systematic Review and Meta-Analysis of NIBS and CIMT for Post-Stroke Motor Impairment

A 2026 systematic review and meta-analysis by Esma Nur Kolbaşı, aggregating data from 10 randomized controlled trials involving 420 stroke patients with a mean age of 59.6 years. The study evaluates the combined effects of active noninvasive brain stimulation (NIBS) and constraint-induced movement therapy (CIMT) on motor impairment and functional ability. Findings suggest low-certainty evidence for modest improvements in upper extremity motor impairment.

Use Cases

• Conducting a meta-analysis on motor impairment outcomes based on Fugl-Meyer Assessment (FMA-UE) scores.
• Comparing intervention efficacy for stroke rehabilitation based on data from 10 randomized controlled trials.
• Assessing the certainty of evidence for combined NIBS and CIMT therapies using GRADE methodology.

Strengths

• Includes data from 10 randomized controlled trials with a total sample size of 420 patients.
• Reports specific statistical results, including a Hedges' g effect size of 0.55 for the FMA-UE outcome.
• Applies the GRADE framework to assess the certainty of the evidence.

Limitations

• The dataset is very small at 289.1 KB, consisting primarily of document files (JPG, DOCX) rather than structured data.
• Row count and column-level documentation are unknown, limiting suitability assessment for computational analysis.
• The evidence synthesized is of low certainty with high heterogeneity, as noted in the review.

Provenance

Source

figshare, authored by Esma Nur Kolbaşı.

Collection Method

Systematic review and meta-analysis of published randomized controlled trials.

Freshness

Last updated 2026-06-02 16:54:59.