In-Cell Photoactivated Porphyrin Demetalation for Reductive Photodynamic Therapy

Xia Wang published a dataset on figshare in 2026 related to photocontrolled metal ion release systems for hypoxic tumor therapy. The data likely contains experimental results on zinc-coordinated porphyrin (ZnPor) undergoing photochemical Zn2+ release and conversion to phlorin for lysosome-targeted hydride therapy. The dataset is stored in a CSV file with a size of 457.0 B.

Use Cases

• Modeling photochemical demetalation kinetics based on porphyrin structures described.
• Analyzing lysosomal dysfunction mechanisms based on the described photoredox cycle involving NADH and ubiquinone.
• Training models to predict hydride donor efficacy under hypoxia using described photoconversion pathways.

Strengths

• Dataset is published under a specific CC-BY-NC-4.0 license, clarifying reuse terms.
• The description provides a detailed scientific context for the likely experimental data.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 457.0 B, indicating limited scope.

Provenance

Source

Xia Wang via figshare

Collection Method

Likely contains experimental results from the described study on photocontrolled porphyrin demetalation.

Freshness

Last updated 2026-04-28 19:15:02; freshness should be verified.