Molecular Structure of a Rhodium Anticancer Complex Targeting Lipid Membranes

A 16.3 KB PDB file containing the molecular structure of a half-sandwich cyclopentadienyl Rh(III) phenylazopyridine anticancer complex. The data was generated by Edward C. Lant using an integrated multimodal imaging workflow and published in March 2026.

Use Cases

• Analyze the 3D molecular structure to model supramolecular interactions with glycerophosphorylcholine lipids.
• Use the atomic coordinates for Density Functional Theory (DFT) modeling of complex-lipid interactions.
• Investigate the structural basis for the complex's accumulation in plasma membranes and lipid droplets.

Strengths

• Data is derived from an integrated multimodal imaging workflow combining cryogenic super-resolution fluorescence microscopy, soft X-ray tomography, Orbitrap secondary ion mass spectrometry, and inductively coupled plasma-mass spectrometry.
• The PDB format provides a standard, machine-readable representation of the 3D molecular structure.

Limitations

• The dataset is extremely small (16.3 KB), containing only a single molecular structure, which limits statistical or comparative analysis.
• No experimental raw data, quantitative measurements, or biological replicates are included in this file.

Provenance

Source

figshare

Collection Method

Integrated multimodal imaging workflow and computational modeling.

Time Range

null

Freshness

Last updated March 2026.

Geography

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