Spontaneous and Evoked EEG Signal Diversity in Ketamine-Induced Psychedelic States

High-density 62-channel EEG recordings from 10 healthy volunteers before and during sub-anaesthetic ketamine administration. The dataset includes spontaneous brain activity and responses evoked by transcranial magnetic stimulation (TMS), with signal diversity assessed using perturbational complexity index (PCI), Lempel Ziv complexity (LZc), amplitude coalition entropy (ACE), and synchrony coalition entropy (SCE). The research was conducted by Nadine Farnes at the University of Oslo.

Use Cases

• Compare spontaneous EEG signal diversity (LZc, ACE, SCE) between normal wakefulness and ketamine-induced states.
• Investigate the relationship between TMS-evoked complexity (PCI) and altered states of consciousness.
• Analyze the correlation between increased spontaneous signal diversity and subjective assessments of altered consciousness.
• Examine the effect of eyes-open versus eyes-closed conditions on spontaneous EEG signal diversity during ketamine influence.

Strengths

• Data was collected using high-density 62-channel EEG, providing detailed spatial resolution.
• Within-subject design with 10 healthy volunteers allows for controlled comparison of brain states.
• Multiple established signal diversity measures (PCI, LZc, ACE, SCE) were applied to both spontaneous and evoked activity.

Limitations

• Row count and sample size are unknown, which may limit suitability assessment for large-scale modeling.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

University of Oslo (via paperswithcode)

Collection Method

Experimental recordings from an open-label within-subject study.