Mpox Virus Respiratory Shedding in Macaques with Viral Load Measurements

A 2026 study by Zhaoliang Chen monitored respiratory viral shedding in macaques experimentally infected with Clade IIb Mpox virus. The dataset includes measurements of viral load in exhaled particles and ambient air, peaking at 1.58 × 10^10 copies/macaque/hour and 1.9 × 10^7 copies/L respectively 11 days post-infection. It provides evidence supporting airborne transmission, with coarse particles (>7 μm) carrying most of the infectious virus.

Use Cases

• Modeling viral shedding kinetics based on time-series data post-infection
• Analyzing particle size distribution of virus-laden respiratory emissions
• Comparing viral load between exhaled particles and ambient air samples
• Investigating the role of coarse vs. fine particles in airborne transmission

Strengths

• Includes specific viral load measurements (e.g., 1.58 × 10^10 copies/macaque/hour) for quantitative analysis
• Data collection from a controlled experimental infection model allows for precise timing (e.g., 11 days post-infection peak)
• Distinguishes between viral copies in exhaled particles and ambient air, and between coarse (>7 μm) and fine particle fractions

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Data is from an animal model (macaques); direct applicability to human transmission may require further validation

Provenance

Source

Zhaoliang Chen via figshare

Collection Method

Experimental monitoring of macaques infected with Clade IIb Mpox virus

Freshness

Last updated 2026-04-17 02:20:25; freshness should be verified