Vancomycin AUC and Acute Kidney Injury Incidence in 180 Patients

A clinical study dataset investigating the relationship between early vancomycin exposure and acute kidney injury. The data includes 180 enrolled patients, with 29 (16.1%) developing AKI, and groups patients based on measured AUC0–48h values. The research was authored by Yuta Ibe and last updated on figshare in April 2026.

Use Cases

• Modeling the risk of acute kidney injury based on cumulative vancomycin AUC values.
• Validating therapeutic drug monitoring thresholds for vancomycin administration.
• Analyzing hazard ratios for different drug exposure groups in a clinical cohort.

Strengths

• Includes specific, reported patient counts (180 enrolled, 29 AKI cases).
• Provides concrete statistical results (hazard ratios and confidence intervals).
• Released under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data files are in DOCX and TIF formats, which may require conversion for analysis.

Provenance

Source

figshare

Collection Method

Clinical study evaluating patients receiving vancomycin.

Time Range

The study period is not specified in the provided metadata.

Freshness

Last updated 2026-04-20 05:43:37; freshness should be verified.

Geography

The geographic coverage is not specified in the provided metadata.