Rhodium-Catalyzed Lactone Synthesis via C–H Functionalization

A 40.9 MB dataset from figshare, uploaded by Bijaya Bagale and last updated on 2026-05-12. It contains experimental results on intramolecular C–H functionalization using rhodium catalysts with α-alkyl-α-diazoesters. The data likely includes yields and diastereoselectivity metrics for synthesizing various lactones.

Use Cases

• Modeling reaction yields based on catalyst and substrate structures mentioned in the description
• Analyzing diastereoselectivity trends for γ, δ, and ε-lactone synthesis
• Benchmarking computational methods against experimental results for late-stage functionalization

Strengths

• Dataset size is 40.9 MB, indicating a substantial amount of structured experimental data.
• Description reports excellent yields and diastereoselectivity for alkyl γ-lactones and good yields for other lactones.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

Experimental chemistry results from catalytic reactions.

Freshness

Last updated 2026-05-12 09:08:34; freshness should be verified.