LC-MS Metabolic Flux and Metabolomics Data for HCT116 Colorectal Cancer Cells

LC-MS-based metabolic flux and metabolomics data from control and SMC4-attenuated HCT116 colorectal cancer cells, including raw mass spectrometry files and processed results. The 958.7 MB repository contains raw data underlying all figures from an associated Cell Metabolism article. Author xuedan sun published the dataset under a CC-BY-4.0 license on figshare.

Use Cases

• Analyzing metabolic flux changes in colorectal cancer cells based on isotope tracing results using 1,2-¹³C-D-glucose
• Comparing metabolite abundance between control and SMC4-attenuated cell lines based on processed metabolite abundance matrices
• Validating computational models of cancer metabolism based on raw mass spectrometry files and lactate isotopologue analysis

Strengths

• Includes raw mass spectrometry files (WIFF, SCAN, ~IDX2 formats) alongside processed data (XLSX, CSV), enabling reproducibility
• Contains data underlying all figures from a peer-reviewed Cell Metabolism article, linking results directly to source data
• Dataset is 958.7 MB in size, suggesting substantial primary experimental data

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment for specific analytical tasks

Provenance

Source

figshare

Collection Method

LC-MS-based experimental data generated from HCT116 colorectal cancer cell cultures.

Freshness

Last updated 2026-05-20 15:24:54