Research data from a study investigating the antimalarial potential of Poincianella pluviosa leaves. The dataset likely contains results from bioassays against chloroquine-resistant Plasmodium falciparum and cytotoxicity tests on HepG2 cells. The work was conducted by Jacqueline Elis de Souza and published via paperswithcode.
Use Cases
- Compare antimalarial efficacy based on IC50 values for aqueous extract and organic fractions.
- Identify bioactive phenolic compounds based on the reported phenolic profile.
- Evaluate cytotoxicity based on toxicity tests against HepG2 A16 cells.
- Assess renewable sourcing potential based on the comparison of leaves versus stem bark.
Strengths
- Provides specific IC50 values for aqueous extract (6.88 ± 1.64 µg mL-1) and organic fraction (1.83 µg mL-1).
- Reports comparative activity of isolated compounds, such as Ellagic acid (IC50= 0.215 ± 0.007 µg mL-1).
- Includes cytotoxicity assessment against HepG2 A16 cells.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
Provenance
- Source
- Jacqueline Elis de Souza
- Collection Method
- Experimental laboratory study of plant extracts and compounds.