Parkinson's Disease Motor Asymmetry and Axial Burden Under Levodopa and STN-DBS

A retrospective cross-sectional study of 184 Parkinson's disease patients (44 with STN-DBS, 140 without) conducted by Halil Onder. It compares motor asymmetry and axial involvement between treatment groups, with standardized evaluations in medication 'OFF' and 'ON' states. The dataset was last updated on 2026-04-21.

Use Cases

• Compare motor asymmetry between STN-DBS and medically treated patients based on Motor Asymmetry Index (MAI) scores.
• Analyze axial-to-appendicular burden changes under levodopa based on Axial-to-Appendicular Ratio (AAR) calculations.
• Model the effect of disease duration and baseline motor severity on motor domain expression using adjusted analyses.
• Investigate the magnitude of levodopa-induced shifts in motor phenotype across different treatment cohorts.

Strengths

• Includes data from 184 patient evaluations, providing a substantial clinical cohort.
• Contains standardized 'OFF' and 'ON' state assessments for each patient, enabling within-subject analysis.
• Calculates specific clinical indices (MAI and AAR) from MDS-UPDRS-III subscores, offering structured metrics.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 46.9 KB, indicating limited scope and likely summary-level data.

Provenance

Source

figshare, author Halil Onder.

Collection Method

Retrospective cross-sectional study of 184 consecutive PD patients undergoing standardized evaluations.

Freshness

Last updated 2026-04-21 22:20:02; freshness should be verified.