LncRNA 91H Expression and Interaction Data for Colorectal Cancer

A study by Tianyi Gao of the University of Bristol investigated the role of long non-coding RNA 91H in colorectal cancer. The research detected higher expression of lncRNA 91H in CRC tissues and cells compared to normal ones, and found a significant interaction between lncRNA 91H and the protein IGF2BP2. These results suggest a mechanism for promoting IGF2 expression, indicating potential diagnostic and therapeutic targets.

Use Cases

• Identifying potential diagnostic biomarkers for colorectal cancer based on lncRNA 91H expression levels.
• Studying the molecular mechanism of tumor metastasis and invasion linked to lncRNA 91H.
• Investigating RNA-protein interactions, specifically between lncRNA 91H and IGF2BP2, in cancer biology.
• Exploring therapeutic targets by analyzing the pathway regulating IGF2 expression in colorectal cancer.

Strengths

• Data is derived from experimental assays including RNA pull-down and RNA-binding protein immunoprecipitation (RIP).
• Findings are supported by statistical significance (p < .05) for the association between high lncRNA 91H expression and tumor metastasis risk.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.

Provenance

Source

University of Bristol

Collection Method

Experimental study involving assays on CRC tissues and cells.