Ulcerative Colitis Disease Progression in a Norwegian Cohort, 2002–2024

736 incident Ulcerative Colitis cases from the Norwegian HUNT study were followed for a median of 5.3 years. Progression in disease extent occurred most frequently during the first three years after diagnosis, with proctitis cases having the highest annual risk. Female sex and diagnosis after 2010 were associated with a higher risk of progression and more severe disease.

Use Cases

• Modeling disease extent progression over time based on Montreal Classification data.
• Analyzing sex-based differences in disease progression risk.
• Investigating temporal trends in disease severity for cases diagnosed after 2010.
• Estimating the proportion of patients transitioning from proctitis to more extensive colitis.

Strengths

• Includes 736 validated patient cases from a population-based cohort.
• Provides a median follow-up time of 5.3 years with interquartile range.
• Reports specific progression rates, such as a 7.5% annual risk for proctitis cases.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is 395.3 KB, indicating a limited scope of data.

Provenance

Source

Trøndelag Health Study (HUNT), Norway.

Collection Method

Incident cases identified among adult HUNT participants and validated through hospital records.

Time Range

2002–2024.

Freshness

Last updated 2026-05-21 02:46:50; freshness should be verified.

Geography

Norway (Trøndelag region).