Long-Term HIV Treatment Outcomes for 441 Patients Switching to BIC/FTC/TAF

441 people with HIV (PWH) were included in this observational retrospective real-life study, with 318 being INSTI-experienced and 123 INSTI-naïve. The data, authored by Antonio Cianciaruso and updated in April 2026, presents a longitudinal analysis of immunological, lipidic, hepatic, and virological parameters over a median follow-up of 181 weeks.

Use Cases

• Analyzing immunological and lipidic parameter improvements based on the 12-month follow-up data mentioned in the description
• Comparing treatment durability and discontinuation rates based on prior INSTI experience described in the cohort
• Evaluating virological efficacy based on the subset of patients with detectable viral loads at switch
• Assessing hepatic and renal safety profiles based on reported stable hepatic profiles and eGFR changes

Strengths

• Includes 441 patient records with a clear breakdown of 318 INSTI-experienced and 123 INSTI-naïve individuals
• Provides longitudinal data with a median follow-up duration of 181 ± 66 weeks
• Reports specific outcome metrics for immunological, lipidic, hepatic, and virological parameters

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data is from a monocentric cohort, which may limit generalizability

Provenance

Source

figshare

Collection Method

Observational retrospective real-life study from a monocentric cohort

Time Range

Median follow-up of 181 ± 66 weeks (approximately 3.48 ± 1.27 years)

Freshness

Last updated 2026-04-09 18:54:23; freshness should be verified

Geography

Monocentric cohort; specific location not stated