Long-term results of surgical ventricular reconstruction and comparison with the Surgical

Mario Gaudino and colleagues from Cornell University published a 2022 study comparing long-term results of surgical ventricular reconstruction (SVR). The dataset likely contains individual patient data from 725 patients at San Donato Hospital and 501 patients from the STICH trial, with follow-up data up to 4 years. The study analyzed outcomes including all-cause mortality and left ventricular end-systolic volume index (LVESVI).

Use Cases

• Compare long-term mortality outcomes between different surgical cohorts based on institutional volume.
• Analyze the relationship between postoperative left ventricular end-systolic volume index (LVESVI) and patient survival.
• Model the effect of patient age and baseline LVESVI on surgical outcomes for ischemic cardiomyopathy.
• Benchmark clinical trial results against high-volume institutional practice data.

Strengths

• Includes data from 1,226 total patients (725 from San Donato Hospital and 501 from the STICH trial).
• Provides long-term follow-up data, with mortality and LVESVI reduction results reported at 4 years.
• Uses individual patient data and propensity score weighting for cohort comparison.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Data may reflect geographic and institutional bias inherent to the specific hospitals studied.

Provenance

Source

Cornell University (author Mario Gaudino), San Donato Hospital (Milan), and the STICH trial.

Collection Method

Clinical study comparing patient cohorts using inverse probability treatment-weighted Cox regression.

Time Range

Study published in 2022; specific patient enrollment period not stated.

Geography

Patients from San Donato Hospital in Milan, Italy, and the multi-center STICH trial.