Hematological Ratios for Inflammation in Ascending Thoracic Aortic Aneurysm Patients

105 patients diagnosed with ascending thoracic aortic aneurysm (ATAA) and 100 healthy controls were studied retrospectively in 2014. The research evaluated four calculated hematological ratios—MPVPCR, MPVLR, RDWPCR, and MPV—as potential markers of inflammatory activity. MPVPCR showed the highest sensitivity (80%) and RDWPCR the highest specificity (72%) in ROC analysis.

Use Cases

• Predicting inflammatory status in ATAA patients based on hematological ratio levels mentioned in the description
• Comparing biomarker performance (sensitivity/specificity) for disease classification as described in the ROC analysis
• Investigating relationships between platelet, lymphocyte, and neutrophil counts and aneurysm pathology as outlined in the study results

Strengths

• Includes a control group of 100 healthy individuals for comparison
• Reports specific statistical significance levels (P-values) for key biomarker differences
• Provides performance metrics (80% sensitivity, 72% specificity) for key ratios from ROC analysis

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download
• Last update date is unknown; freshness unverified

Provenance

Source

Yusuf Kenan Tekin via paperswithcode

Collection Method

Retrospective clinical study of patients admitted to an emergency department

Time Range

Data collected in 2014