Medial Olivocochlear Function and Genotoxicity in Students from Tobacco-Producing Region

46 schoolchildren participated in an observational, prospective, cross-sectional study comparing auditory function and genotoxic biomarkers. The study group consisted of 21 normo-hearing students residing in a tobacco-producing region, while the control group had 25 normo-hearing students from non-rural areas. The dataset was created by Letícia Regina Kunst and is available via paperswithcode.

Use Cases

• Compare medial olivocochlear system function based on distortion product otoacoustic emission suppression results between exposed and control groups.
• Analyze genotoxic damage levels based on comet assay, micronucleus test, and fluorimetric DNA quantification assay results.
• Investigate potential associations between auditory suppression effects and the outcomes of the three genotoxic biomarkers.

Strengths

• Includes data from 46 participants, allowing for a case-control comparison.
• Measures multiple endpoints: auditory function and three distinct genotoxic biomarkers (comet assay, micronucleus test, fluorimetric DNA quantification).
• Study design is explicitly described as observational, prospective, and cross-sectional.

Limitations

• Row count and specific column-level documentation are absent; field semantics must be inferred after download.
• Last update date is unknown; freshness unverified.
• The sample size of 21 in the study group may limit statistical power for some analyses.

Provenance

Source

Letícia Regina Kunst via paperswithcode

Collection Method

Observational, prospective, cross-sectional study with clinical assessments and laboratory biomarker tests.

Geography

Tobacco-producing region (study group) and non-rural area (control group), specific location unknown.