Metabolome and Excretory/Secretory Metabolites of Anisakis Larvae Under Drug Treatment

A metabolomic database from a 2020/37/N/NZ9/03312 grant-funded study. It contains data on metabolic alterations in L3 larvae of Anisakis simplex induced by albendazole, ivermectin, and pyrantel, as well as their excretory/secretory metabolites. Data was generated using ultra-performance liquid chromatography coupled with mass spectrometry (UHPLC–MS) and analyzed with bioinformatics tools including Gene Ontology and KEGG pathway enrichment.

Use Cases

• Identify novel antiparasitic drug targets based on altered metabolic pathways in Anisakis larvae.
• Compare the distinct effects of albendazole, ivermectin, and pyrantel on nematode metabolism.
• Analyze excretory/secretory metabolite profiles to understand host-parasite interactions under drug pressure.
• Perform pathway enrichment analysis using the provided GO and KEGG database annotations.

Strengths

• Data generated using UHPLC–MS, a high-resolution analytical technique.
• Includes pathway enrichment analysis using established Gene Ontology and KEGG databases.
• Funded by a specific National Science Centre of Poland grant (2020/37/N/NZ9/03312).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The 19.6 MB file size suggests a relatively small-scale metabolomic dataset.

Provenance

Source

Mateusz Maździarz via figshare

Collection Method

Experimental study using UHPLC–MS on Anisakis simplex L3 larvae treated with drugs.

Freshness

Last updated 2026-05-21 11:11:02; freshness should be verified.