MNS Drug Study: Multi-Omic Data on Antiviral and Anti-Inflammatory Effects

92.5 MB of multi-omics data from figshare details the antiviral and anti-inflammatory effects of the small-molecule nitrovinyl benzodioxole MNS (NSC170724). The dataset includes bulk RNA-seq and ATAC-seq profiling from cellular and mouse infection models across DNA and RNA viruses. Author Yang Zhao published this CC-BY-4.0 licensed dataset in May 2026.

Use Cases

• Analyze transcriptional changes in inflammatory pathways like NF-κB based on RNA-seq data mentioned in the description
• Study epigenetic regulation via chromatin accessibility changes based on ATAC-seq data mentioned in the description
• Evaluate antiviral efficacy across multiple virus types based on mouse infection model data mentioned in the description
• Correlate gene expression with chromatin accessibility based on joint RNA-seq and ATAC-seq analysis mentioned in the description

Strengths

• 92.5 MB of multi-omics data including RNA-seq and ATAC-seq
• Data covers four lethal viral infection models and LPS-induced endotoxic lethality models
• CC-BY-4.0 license allows for broad reuse and sharing

Limitations

• Column-level documentation is absent; field semantics must be inferred after download
• Row count is unknown, which may limit suitability assessment
• Data may reflect experimental bias inherent to the specific cell lines and mouse models used

Provenance

Source

figshare

Collection Method

Experimental data from cell lines and mouse infection models, analyzed via RT-qPCR, ELISA, western blotting, RNA-seq, and ATAC-seq.

Freshness

Last updated 2026-05-14 12:00:07