Mouse Renal Transcriptome Sequencing for IgA Nephropathy (12 Samples)

Mouse renal transcriptome sequencing data from a study characterizing IgA nephropathy (IgAN). The dataset includes 8 IgAN samples and 4 control samples from mice sacrificed at 20 weeks of age. RNA libraries were sequenced by OE Biotech, Inc., Shanghai, China, and the data was uploaded by an author named Qin.

Use Cases

• Identify differentially expressed genes based on transcriptomic changes between IgAN and control mouse samples.
• Validate murine models of IgA nephropathy based on multi-component induction protocol details.
• Perform pathway analysis based on renal transcriptomic data to understand disease progression.

Strengths

• Dataset includes a defined experimental design with 8 disease and 4 control samples.
• Data is shared under a permissive CC-BY-4.0 license.
• The model induction protocol (BSA, CCl₄, LPS) is explicitly described.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is small (10.2 MB), potentially limiting the scope of analysis.

Provenance

Source

figshare, uploaded by author Qin.

Collection Method

Transcriptome sequencing of mouse renal tissue from an induced IgA nephropathy model.

Freshness

Last updated 2026-05-22 07:00:12; freshness should be verified.